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Discover the Best Weight Loss Supplements that work. Browse the latest and most popular weight loss pills, shakes, supplements, snacks and protein shakes at Medical Weight Loss. Research shows that some people taking prescription weight-loss medications lose 10 percent or more of their starting weight. 1 Results vary by medication and by person. Weight loss of 5 to 10 percent of your starting body weight may help improve your health by lowering blood sugar , blood pressure , and triglycerides . See full list on mayoclinic.org